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Scientist working to create "Mirror Life" bio-organism warns other researchers to STOP!

Creating "mirror life" could be one of science's greatest breakthroughs, but some researchers who began the effort are now calling for it to stop.

No mirror-life microorganisms exist. But 38 scientists warned in a paper published in the journal Science that if someone created one and it escaped the lab, it could cause a catastrophic multispecies pandemic.

"We're basically giving instructions of how to make a perfect bioweapon," Kate Adamala, a coauthor of the paper and a chemist who leads a synthetic biology lab at the University of Minnesota, told Business Insider.

As the risks became clear, Adamala ended her lab's efforts to build a mirror cell. Her multiyear grant for that research expired and she decided not to apply for renewal, she said.

Now she and the 37 other researchers are urging other scientists to do the same.

"Although we were initially skeptical that mirror bacteria could pose major risks, we have become deeply concerned," they wrote in the paper.

Mirror biology takes a fundamental rule of life on Earth, called chirality, and flips it.

Chirality is the simple fact that molecules — like sugars and amino acids — point in one of two directions. They are either right-handed or left-handed.

For some reason, though, life uses only one chiral form of each molecule. DNA, for example, uses only right-handed sugars for its backbone. That's why it twists to the right.

In mirror biology, scientists aim to create living cells where all the chirality is flipped. Where natural life uses a right-handed peptide to build proteins, mirror life would use the same peptide in its left-handed form.

Adamala's research focused on making mirror peptides, which can help create longer-lasting pharmaceuticals.

The long-term goal of that research was a full mirror cell. Mirror cells could help prevent contamination in bioreactors that use bacteria for green chemical manufacturing because, in theory, they wouldn't interact with natural microorganisms.

"You could have this perfect bioreactor that can just sit there and you can stick your finger into it and you're not going to contaminate it," Adamala said. "That's also precisely the problem."

A mirror bacteria could bypass the natural checks and balances of life, like competing with other bacteria or battling our immune systems.

Adamala said "the death sentence" for her mirror-cell research came when she spoke to immunologists. They explained that for humans, other animals, and plants, immune-system activation depends on chirality.

Immune cells recognize pathogens' proteins, but they wouldn't detect the inverse versions of those proteins that mirror cells would use.

A mirror pathogen "doesn't interact with the host," Adamala said. "It just uses it as a warm incubator with a lot of nutrients."

If a mirror bacteria escaped the lab, it could cause slow, persistent infections that couldn't be treated with antibiotics (because those, too, rely on chirality).

Because they wouldn't face immune resistance, mirror bacteria wouldn't need to specialize in infecting corn, or goats, or birds.

"It would be a disease of anything that lives that can be infected," Adamala said.

In the worst-case scenario, a mirror bacteria would multiply endlessly, unfettered. It would take over its hosts and eventually kill them. It would destroy crops. It would have no predators. It would overwhelm entire ecosystems, swapping out portions of our natural world for a new mirror world.

Adamala estimates that the world's first mirror bacteria is still about a decade away. She argues that's exactly why the research should stop now, before it builds all the tools that someone could use to make that final leap.

"No one can do it on their own right now," Adamala said. "The technology is not mature enough, which means we're pretty well safeguarded against someone crazy enough to say, 'I'll just go do it.'"

In the meantime, Adamala and the other paper authors invited more research on and scrutiny of the risks they identified.

"If someone does prove us wrong, that would make me really happy," she said.

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by Anonymousreply 9December 21, 2024 11:29 PM

Welp.

I'd say this is exactly what we need right about now.

We need to stop this second Trump Administration.

The first global pandemic ended Trump's first reign of terror.

Hopefully, this second "mirror bio weapon" pandemic will end his second reign of terror.

by Anonymousreply 1December 20, 2024 11:21 PM

[quote]It just uses it as a warm incubator with a lot of nutrients

Much like my asshole.

by Anonymousreply 2December 20, 2024 11:23 PM

Scientists will never learn.

They just keep pushing, and pushing, and pushing their research to the limits.

Much like Oppenheimer, who had no idea how his research would play out.

He could easily have ignited the atmosphere and destroyed the world, if his experiment had failed.

But they went ahead with it any way.

This is the same thing.

The researchers (in their relentless quest for knowledge, much like apes flinging poo at a wall) will keep going with their research.

And they won't be satisfied until they kill everyone.

by Anonymousreply 3December 20, 2024 11:27 PM

The Stand come to life.

by Anonymousreply 4December 20, 2024 11:31 PM

Except of course R3 the part where she didn’t pursue continued funding and she and other scientists are calling for no more research for anyone in the field.

Responsible scientists can and sometimes do self-regulate.

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by Anonymousreply 5December 21, 2024 1:27 AM

This is our E.L.E.

by Anonymousreply 6December 21, 2024 10:20 PM

Leonard his ilk have been gleefully hoping for this, too, r6.

They think their ilk gotten loot will protect them from bacteria.

by Anonymousreply 7December 21, 2024 11:18 PM

The only possibility of survival would be uploading your brain to a computer. If you count that as survival, which he might. But then why all the baby mammas?

by Anonymousreply 8December 21, 2024 11:22 PM

Wouldn't this be more like The Thing?

by Anonymousreply 9December 21, 2024 11:29 PM
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